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Age-related Macular Degeneration and Complement Factor H

Organizers: Frederick Ferris and Emily Chew

Recent research by several groups showed the association of age-related macular degeneration (AMD) with complement factor H (CFH). This discovery may lead to insight into the pathogenesis of AMD and possible new strategies for both prevention and treatment of AMD, a disease of significant public importance. This Course features lead investigators presenting their data and a panel discussion of the future of this research. Experts in the field of CHF, immunology, and genetics will also contribute.

Sessions include:

    What is AMD?
    Presented by:
    Albert O. Edwards, MD, PhD
    Institute for Retina Research and Dallas Eye Care Associates
    Presbyterian Hospital of Dallas
    Running time: 00:20:36
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    Methodological Approaches to Genetic Studies of Ocular Disease
    Presented by:
    Jonathan L. Haines, PhD
    Center for Human Genetics Research
    Vanderbilt University Medical Center
    Running time: 00:17:19
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    Identification of CFH as a Major Risk Gene for Macular Degeneration
    Presented by:
    Margaret Pericak-Vance, PhD
    Duke Center for Human Genetics
    Duke University Medical Center
    Running time: 00:16:44
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    Age-Related Macular Degeneration & the Complement System
    Presented by:
    Gregory Hageman
    Department of Ophthalmology and Visual Sciences
    University of Iowa Center for Macular Degeneration
    Running time: 00:17:49
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    The Role of Factor B in AMD
    Presented by:
    Rando Allikmets
    Departments of Ophthalmology and Pathology and Cell Biology
    Columbia University, New York
    Running time: 00:16:15
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    Understanding Macular Degeneration as a Complex Disease
    Presented by:
    Michael Dean
    Running time: 00:16:20
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    A Genomic Perspective of Complement Factor H Association with Age-Related Macular Degeneration
    Presented by:
    Anand Swaroop
    Gonçalo Abecasis
    Running time: 00:19:58
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    Relating Factor H Structure to Its Role in Regulating the Complement System
    Presented by:
    Véronique Frémeaux-Bacchi
    Department of Immunology
    Laboratory of Hument Complement Deficiencies
    Hôpital Européen Georges Pompidou, Paris
    Running time: 00:16:33
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    Update on Age-Related Macular Degeneration and Complement Factor H
    Presented by:
    Dean Bok, PhD
    Jules Stein Eye Institute
    University of California, Los Angeles
    Running time: 00:30:45
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